The choice is physio-logical
Non Avian Derived {NAD}
Non Heat Degraded {NHD}
Sodium hyaluronate
Non Heat Degraded {NHD}
Sodium hyaluronate
Professional healthcare
HA viscosupplementation references
This section provides a selection of references and publications on visco-supplementation. You will find official guidelines, meta-analysis, reviews and articles on this treatment modality.
This section provides a selection of references and publications on visco-supplementation. You will find official guidelines, meta-analysis, reviews and articles on this treatment modality.
GUIDELINES
EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT)
Jordan & Al., 2003
Jordan & Al., 2003
Recommendations for the Medical Management of Osteoarthritis of the Hip and Knee
American College of Rheumatology, 2000
American College of Rheumatology, 2000
OARSI 2008 recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
META-ANALYSIS AND REVIEWS
Viscosupplementation for the treatment of osteoarthritis of the knee - The Cochrane collaboration (Abstract)
Bellamy & Al., 2005
Bellamy & Al., 2005
Hylan versus hyaluronic acid for osteoarthitis of the knee: a systematic review and meta-analysis
Reichenbach & Al., 2007
Reichenbach & Al., 2007
Intra-articular Hyaluronic Acid (Viscosupplementation) for Knee Osteoarthritis
Canadian Agency for Drugs and Technologies in Health, 2006
Canadian Agency for Drugs and Technologies in Health, 2006
Therapeutic Effects of Hyaluronic Acid on Osteoarthritis of the Knee. A Meta-Analysis of Randomized Controlled Trials
Chen-Ti Wang & Al., 2004.
Chen-Ti Wang & Al., 2004.
MODE OF ACTION
The Physical properties of Synovial Fluid and the Special Role of Hyaluronic Acid
Balazs, 1974
Balazs, 1974
Potential Mechanism of Action of Intra-articular Hyaluronan Therapy in Osteoarthritis: Are the effects Molecular Weight Dependent?
Ghosh, 2002
Ghosh, 2002
CLINICAL DATA
Potential Structural effects
Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee
Listrat & Al., 1997
Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: Clinical and morphological study
Frizziero & Al., 1998
Frizziero & Al., 1998
Role of molecular weight
Efficacy and Safety of Intraarticular Hylan or Hyaluronic Acids for Osteoarthritis of the Knee
Juni & Al., 2007
Comparison between high and low molecular weight hyaluronates in knee osteoarthritis patients: open-label, randomized, multicentre clinical trial
PB Lee & Al., 2006
PB Lee & Al., 2006

